Some veins are harder to reach or have unusual shapes that make other approaches less effective. In these cases, we may recommend an injectable foam treatment called Varithena. At Physicians Vein Clinics, we have a range of treatments that are all minimally invasive, performed right in the office and allow you to go back to work right away. If you need relief from unhealthy veins, give us a call at 888-782-8346 to learn more about our treatments.

What Is Varithena?

Varithena is a minimally invasive, non-surgical treatment used to address abnormal veins. It is an FDA-approved prescription foam designed to treat symptoms associated with vein disease.

Guided by ultrasound imaging, Varithena is injected directly into the affected veins, where the foam works to collapse and seal the vessel. Blood flow is then naturally redirected to healthier veins, improving circulation and reducing symptoms over time.

Benefits of Varithena®

  • Minimally invasive, non-surgical
  • High success rate, up to 94%
  • Office-based procedure (no hospital stay)
  • No general anesthesia
  • No downtime
  • Fewer side effects than traditional vein “stripping”
  • Improves undesirable appearance of veins

How to Prepare for Varithena

  • Bring your compression stockings with you for each appointment.
  • Bring comfortable shoes for walking.
  • Avoid using lotions on your legs the day of your Varithena session.
  • Drink at least 64oz of water and avoid any alcohol the day prior to your Varithena session.
  • Drink 32oz of water the day of your Varithena session.
  • Report any medication, allergies, or changes in your medical condition prior to your session.
  • Avoid air travel for 1 week following your Varithena session.

What Happens During Varithena

  • Treatment with Varithena doesn’t require any incisions or general anesthesia. It usually takes the doctor less than an hour to administer Varithena.
  • The doctor administers a small amount of Varithena through a catheter or by direct injection into the malfunctioning vein.
  • The Varithena microfoam fills and treats the desired section of vein.
  • The diseased vein collapses, and the microfoam is deactivated.
  • When the malfunctioning vein collapses, blood flow shifts to healthy veins.

What Happens After Varithena

  • Expect bruising, which can be extensive. This is temporary and resolves gradually over several weeks.
    Soreness or tenderness at injection sites is normal for 1-2 days. You may experience a stinging or burning sensation that lasts minutes to hours directly following the procedure. This is a sign that the medication is working in the vein. Walking and wearing prescription-grade compression stockings (20-30mmHg graduated compression or higher) are recommended.
  • Blood can become trapped in closing veins as they heal, and this can cause tender, sometimes lumpy areas in treated veins. If you develop tender spots, you may want to begin taking an over-the-counter pain medication such as acetaminophen (Tylenol) or an NSAID (Ibuprofen, Advil, Motrin, Aleve, Naproxen). NSAIDs tend to be more effective at reducing the inflammation that causes pain.
  • Always check with your primary care provider before taking any new medication.
  • Consult the medication packaging instructions regarding maximum dosing or ask your pharmacist. Using this medication daily for 1-2 weeks can help reduce inflammation and speed your recovery, even if it does not take the pain away entirely. Expect this pain to improve gradually over several weeks.
    Continue to wear your compression stockings during the day and walk a minimum of 40 min throughout the day as long as you are having discomfort. Call the office for an appointment if you are having significant pain or extreme discomfort. An ultrasound evaluation may be recommended to verify the source of your pain and guide your treatment.
  • Lasting numbness in the treatment area is not uncommon. This gradually improves over weeks to months.
  • Brown, tan or yellow staining of the skin (hyperpigmentation) may occur over the treated vein as it is being absorbed. This will lighten gradually over 6-18 months.
  • Generally, you will notice improvement in your symptoms over several weeks.
  • Optimal cosmetic improvement generally takes 6-12 months.
  • Vein disease is chronic and progressive. New veins will become unhealthy over time. Expect to follow up with your vein specialists at Physicians Vein Clinics.

Post-Treatment Instructions:

  • After Varithena, a compression stocking will be applied. After walking for 10-20 minutes, you will be able to drive yourself home.
  • You will be instructed to wear compression stockings continuously for 2 days. Thereafter, you will put your stockings on in the morning and take them off at night for 12 additional days. You do not need to wear stockings while showering.
  • You may resume most of your regular activities immediately, excluding running, jumping, and other strenuous activities that involve your core muscle group (torso area). Do not lift more than 40 pounds for 1 week. You may resume normal workouts after 1 week.
  • Avoid air travel for 1 week following a Varithena session.
  • Avoid hot tubs, baths, lakes or swimming pools for 1 week.
  • You are encouraged to walk 30-60 minutes per day.

Schedule Your Varithena Consultation

If varicose veins are causing discomfort or interfering with your daily life, Varithena may be an effective treatment option. At Physicians Vein Clinics, our board-certified vein specialists use advanced ultrasound imaging to determine whether Varithena is right for you and guide you through every step of care.

Schedule your free screening or call to speak with our care team and take the next step toward healthier, more comfortable legs.

FAQs About Varithena

Is Varithena® effective?

In clinical studies, the majority of patients treated with Varithena saw improvements in related symptoms, including leg heaviness, achiness, swelling, and itching after just one treatment. In an assessment by both patients and physicians, the majority of patients also experienced an improvement in vein appearance.

I have numbness of the skin on my treated leg, should I be worried?

Numbness is not uncommon after vein procedures. Skin nerves can be affected during the procedure which can cause numbness, tingling or “pins and needles”. This is not worrisome and generally improves gradually over several months.

I have noticed new veins on the surface of my treated leg. Is this normal?

Yes, new veins can appear when unhealthy veins are treated. These are existing veins that become congested and visible. Sometimes they are so small and numerous that they give a “matting” appearance. Matting typically improves or completely resolves within 6-12 months.

When can I shower after my procedure?

You can shower the day following your procedure.

I have a history of migraine headaches, and I developed a migraine after my vein treatment. Is this related to the procedure?

Migraines can be triggered by vein procedures. Treat these as you normally would. You may have migraines with future treatments and should plan to have migraine medication on hand at the time of treatment.